http://www.polygenicpathways.co.uk/schizrisk.htm - May 19, 2013 7:42:36 AM - Mar 7, 2011 3:38:05 PM
(Pathway GWAS RDH8 ACVR1, PSMD9 KCNAB1, KCNQ2, SLC17A3, ARCN1, COG7, STAB2, LRPAP1, STAB1, CXCL16, COL4A4 )EXOSC3
May 16, 2013
- A metabolomics plasma study identified higher concentration of ornithine and lower concentrations of arginine, glutamine, histidine and phosphatidylcholine ae C38:6 in schizophrenic patients He et al, 2012
May 11, 2013
PHOX2B PHTF2
ADAMTSL3FASRAI1MYO5BHPS4AS3MTCNNM2NT5C2AMBRA1
- Maternal cytomegalovirus or toxoplasma gondii infection Blomström et al, 2012
- The use of aspirin, but not Paracetamol or other analgesics, during pregnancy has been linked to later psychosis in the offspring
- Acute relapse in schizophrenia has been associated with urinary tract infections Miller et al, 2013
- High levels of anti-gliadin IgG in the maternal circulation associated with risk for the development of nonaffective psychosis in the offspring Karlsson et al, 2012
Biochemistry, biomarkers and pathology
- miR-34a, miR-449a, miR-564, miR-432, miR-548d, miR-572 and miR-652 as biomarkers in mononuclear leukocytes Lai et al, 2011
- Elevated 3-hydroxykynurenine levels in plasma Condray et al, 2011
- Schizophrenia patients frequently display reduced niacin flush responses Lien et al, 2013
Autoantibodies and antibodies in schizophrenia
- Autoantibodies to 60Kd proteins possibly including HSP60, MYC and PAM
- IgG antibodies to Saccharomyces cerevisiae in recent onset schizophrenia patients , correlating with food antigen antibodies (bovine milk casein, wheat-derived gluten): Anti-food antigen antibodies were correlated to antibodies against Toxoplasma gondii Severance et al, 2012
April 22, 2013
View Stats March 24, 2013
- Hyperthermia in utero (related to maternal influenza infection) Edwards, 2007
- Antibodies to retroviruses (Mason-Pfizer monkey virus and murine leukemia virus) in first epidode schizophrenic patients Dickerson et al, 2012
- Increased antibody titres for Chlamydia trachomatis Krause et al, 2010
- Increased levels of smallpox antibodies in a Russian study Vasil'eva et al, 1986
January 21, 2013
- Hepatitis E seroprevalence higher in schizophrenic patients in China Xue et al, 2012
- Hallucinogenic mushrooms McDonald 1980
- Scizophrenia incidence peaks in late adolescence ( puberty ) in men and women and following menopause in women Markham, 2012
January 18, 2013
- Mercury related schizophreniforme psychosis Bader , 1952
November 13, 2012